Title:
【発明の名称】脂質代謝疾患の治療に対するピレンゼピン、メチルスコポラミン及び他のムスカリン性受容体アンタゴニストの投与法
Document Type and Number:
Japanese Patent JPH10507159
Kind Code:
A
Abstract:
Disclosed are methods for improving various aberrant metabolic indices in mammals including humans by administration of muscarinic (particularly M1) receptor antagonists alone or in combination with prolactin inhibiting compounds. Preferably the administration takes place at a predetermined time (or, if a combination of muscarinic receptor antagonist and prolactin inhibitor is used, at different predetermined times) during a 24-hour period when the administration is effective (or its effect more pronounced). The invention has application in the treatment of lipid and glucose metabolism disorders.
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Inventors:
Shincotta, Anthony H
Albert H. Mayer
Wilson, John M
Albert H. Mayer
Wilson, John M
Application Number:
JP50262696A
Publication Date:
July 14, 1998
Filing Date:
June 20, 1995
Export Citation:
Assignee:
The General Hospital Corporation, D/B/A Massachusetts General Hospital
The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
International Classes:
A61K31/00; A61K31/13; A61K45/00; A61K31/137; A61K31/15; A61K31/166; A61K31/195; A61K31/221; A61K31/35; A61K31/352; A61K31/40; A61K31/405; A61K31/435; A61K31/439; A61K31/445; A61K31/4515; A61K31/454; A61K31/46; A61K31/475; A61K31/48; A61K31/54; A61K31/5415; A61K31/55; A61K31/551; A61K31/5513; A61K31/695; A61K38/22; A61K45/06; A61P3/04; G01N33/74; (IPC1-7): A61K45/00
Attorney, Agent or Firm:
Masatake Shiga (2 outside)