Title:
【発明の名称】1-アルキル-エルゴリニル-チオ尿素誘導体、その製法およびこれを含有する、中枢性α▲下2▼-受容体-遮断作用を有する薬剤
Document Type and Number:
Japanese Patent JPH0667938
Kind Code:
B2
Abstract:
Novel 1-alkyl ergolinylthiourea derivatives of the general formula wherein R1 is C1-6 alkyl, R2 and R3 are C1-4 alkyl, R4 is hydrogen or C1-4 alkyl and C9--C10 is a single bond or a double bond, and the acid addition salts thereof, with the provision that when R3 and R4 are both ethyl, R1 and R2 are not methyl and acid addition salts thereof are provided; as well as a process for the preparation of these compounds. The compounds are useful as medicinal agents, e.g., for the treatment of mental depression.
Inventors:
Helmut Biele
Gerhard Sauer
Helmut Wuerter
Gerhard Sauer
Helmut Wuerter
Application Number:
JP18356786A
Publication Date:
August 31, 1994
Filing Date:
August 06, 1986
Export Citation:
Assignee:
Schie-Ring Actien Gezershaft
International Classes:
A61K31/48; A61P25/02; A61P25/24; A61P25/26; C07D457/12; (IPC1-7): C07D457/12; A61K31/48
Attorney, Agent or Firm:
Toshio Yano (1 outside)
Next Patent: ABORT CAUSE DISPLAY SYSTEM