Title:
【発明の名称】5HT▲下2▼受容体の選択的遮断剤
Document Type and Number:
Japanese Patent JPH0669951
Kind Code:
B2
Abstract:
Method of blocking 5HT2 without effect on alpha receptors with 1-loweralkyl-6-straight chain alkyl-8β-hydroxycyclo- alkyloxycarbonylergolines of the formulawherein R is primary or secondary C1-C8 alkyl, CH2C2-C4 alkenyl, C3-C8 cycloalkyl or C3-C6 cycloalkyl-substituted C1-C5 primary or secondary alkyl, the total number of carbon atoms in R not to exceed 8; R1 is C1-C4 straight chain alkyl or allyl, and R2 is hydroxy C5-C7 cycloalkyl, or a pharmaceutically-acceptable salt thereof.
Inventors:
Marlen Luis Cohen
Ray Ward Fuller
William Lee Garblet
Katharine Rose Whitten
Ray Ward Fuller
William Lee Garblet
Katharine Rose Whitten
Application Number:
JP23425486A
Publication Date:
September 07, 1994
Filing Date:
September 30, 1986
Export Citation:
Assignee:
Lee-Lee Lili-and Company-
International Classes:
C07D457/04; A61K31/48; A61P9/08; A61P9/12; A61P25/04; A61P25/18; A61P25/24; A61P25/26; A61P43/00; (IPC1-7): A61K31/48; A61K31/48
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)
Next Patent: ELECTRONIC MAIL COMMUNICATION SYSTEM