Title:
【発明の名称】活性酸素抑制剤
Document Type and Number:
Japanese Patent JP2829451
Kind Code:
B2
Abstract:
A superoxide radical inhibitor containing, as an effective ingredient, an azole derivative represented by the general formula (1), Äwherein R<1> represents a phenyl group which may have 1-3 lower alkoxy groups as substituent(s) on the phenyl ring, a phenyl group having a lower alkylenedioxy group, or the like; R<2> represents a hydrogen atom, a phenyl group, a halogen atom, a lower alkoxycarbonyl group, a lower alkyl group, an amino-lower alkyl group which may have a lower alkyl group as a substituent, a dihydrocarbostyril group, or the like; R<3> represents a group of the formula, (R<4B> represents a hydroxyl group, a carboxy group, a lower alkenyl group or a lower alkyl group. m represents 0, 1 or 2); X represents a sulfur atom : Ü or a salt thereof.
Inventors:
Chihiro Masatoshi
Komatsu Hajime
Tominaga Michiaki
Youichi Yabuuchi
Komatsu Hajime
Tominaga Michiaki
Youichi Yabuuchi
Application Number:
JP34249591A
Publication Date:
November 25, 1998
Filing Date:
November 29, 1991
Export Citation:
Assignee:
Otsuka Pharmaceutical Co., Ltd.
International Classes:
A61K31/42; A61K31/415; A61K31/4184; A61K31/421; A61K31/423; A61K31/425; A61K31/426; A61K31/427; A61K31/428; A61K31/44; A61K31/4439; A61K31/445; A61K31/454; A61K31/47; A61K31/4709; A61K31/495; A61K31/496; A61K31/50; A61K31/5025; A61K31/505; A61K31/535; A61K31/5355; A61K31/5377; A61K31/54; A61K31/541; A61K31/66; A61K31/695; A61K31/70; A61K31/7028; A61K31/7034; A61K31/7056; A61P1/00; A61P1/16; A61P3/00; A61P3/10; A61P9/00; A61P9/08; A61P9/10; A61P13/02; A61P13/12; A61P15/00; A61P19/02; A61P25/28; A61P29/00; A61P37/00; A61P43/00; C07D207/335; C07D235/26; C07D263/30; C07D263/32; C07D263/34; C07D263/52; C07D263/56; C07D277/20; C07D277/22; C07D277/24; C07D277/26; C07D277/28; C07D277/30; C07D277/32; C07D277/56; C07D277/60; C07D277/68; C07D409/04; C07D409/14; C07D413/04; C07D417/04; C07D417/14; C07D498/04; C07D513/04; C07F7/18; C07F9/6539; C07H13/04; C07H15/203; C07H15/26; (IPC1-7): C07D417/04; A61K31/425
Domestic Patent References:
| JP471469A | ||||
| JP5461936A | ||||
| JP5511579A | ||||
| JP60230147A | ||||
| JP6140276A | ||||
| JP6110557A | ||||
| JP6222493A | ||||
| JP62252780A | ||||
| JP63192755A | ||||
| JP2171280A | ||||
| JP4615935B1 |
Other References:
【文献】Chemical Abstracts 第66巻要約番号96203(1967)
【文献】Chemical Abstracts 第70巻要約番号11630b(1969)
【文献】Chemical Abstracts 第71巻要約番号112921(1969)
【文献】Chemical Abstracts 第82巻要約番号170971(1975)
【文献】Chemical Abstracts 第85巻要約番号159962(1976)
【文献】Chemical Abstracts 第86巻要約番号55326(1977)
【文献】Chemical Abstracts 第94巻要約番号15628(1981)
【文献】Chemical Abstracts 第96巻要約番号20015(1982)
【文献】Chemical Abstracts 第101巻要約番号7145(1984)
【文献】Chemical Abstracts 第109巻要約番号22883(1988)
【文献】Chemical Abstracts 第70巻要約番号11630b(1969)
【文献】Chemical Abstracts 第71巻要約番号112921(1969)
【文献】Chemical Abstracts 第82巻要約番号170971(1975)
【文献】Chemical Abstracts 第85巻要約番号159962(1976)
【文献】Chemical Abstracts 第86巻要約番号55326(1977)
【文献】Chemical Abstracts 第94巻要約番号15628(1981)
【文献】Chemical Abstracts 第96巻要約番号20015(1982)
【文献】Chemical Abstracts 第101巻要約番号7145(1984)
【文献】Chemical Abstracts 第109巻要約番号22883(1988)
Attorney, Agent or Firm:
Eiji Saegusa (2 others)