Title:
【発明の名称】アミド誘導体
Document Type and Number:
Japanese Patent JP3478827
Kind Code:
B2
Abstract:
PCT No. PCT/GB93/02090 Sec. 371 Date Apr. 11, 1995 Sec. 102(e) Date Apr. 11, 1995 PCT Filed Oct. 8, 1993 PCT Pub. No. WO94/08983 PCT Pub. Date Apr. 28, 1994A novel asymmetric synthesis is provided for preparing optically active amides of formula (A) and their salts. (A) In the formula, X represent -N- or -CH-, R represents a mono or bicyclic aryl or heteroaryl group, R1 is an aryl or heteroaryl radical, and R2 and R3 have specified meanings. The products are useful as 5-HT1A antagonists. Novel diesters of formula D useful as intermediates in the process are also disclosed. (D)
Inventors:
Ashwell, Mark Antony
Application Number:
JP50974494A
Publication Date:
December 15, 2003
Filing Date:
October 08, 1993
Export Citation:
Assignee:
John Weiss and Brother Limited
International Classes:
C07B53/00; C07C233/11; C07D211/22; C07D239/26; C07D239/42; C07D295/145; C07D295/18; C07D295/185; C07D295/14; C07D319/18; (IPC1-7): C07D295/14; C07D211/22; C07D239/26; C07D239/42; C07D295/18; C07D319/18
Domestic Patent References:
| JP4282371A | ||||
| JP311059A |
Other References:
【文献】米国特許2776282(US,A)
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)