Title:
【発明の名称】血管形成阻害剤
Document Type and Number:
Japanese Patent JP2002519377
Kind Code:
A
Abstract:
RGD mimetics which combine a nitroaryl moiety with an arylether/ alpha -aminoacid/guanidine framework exhibit activity as antagonists toward various integrins and as inhibitors of angiogenesis.
Inventors:
Nikola Oh Kyria Kossee
Truh Hiro John
Chivale Kelly
Yanderet Bernd
Godman Simon
Truh Hiro John
Chivale Kelly
Yanderet Bernd
Godman Simon
Application Number:
JP2000557829A
Publication Date:
July 02, 2002
Filing Date:
July 06, 1999
Export Citation:
Assignee:
Merck Patent Gesellschaft Mitt Beschlenktel Haftung
THE SCRIPPS RESEARCH INSTITUTE
THE SCRIPPS RESEARCH INSTITUTE
International Classes:
A61K31/198; A61K31/4168; A61K31/4184; A61K31/495; A61K31/496; A61P35/00; A61P43/00; C07C235/52; C07C247/04; C07C271/22; C07C279/08; C07C279/10; C07C279/12; C07C279/18; C07C311/19; C07D295/20; C07C323/62; C07D233/48; C07D235/14; C07D235/30; C07D295/215; (IPC1-7): C07C279/10; A61K31/198; A61K31/4168; A61K31/4184; A61K31/495; A61P35/00; A61P43/00; C07C279/12; C07C279/18; C07C311/19; C07C323/62; C07D233/48; C07D235/14; C07D235/30; C07D295/20
Attorney, Agent or Firm:
Minoru Nakamura (9 outside)