Title:
【発明の名称】抗菌剤
Document Type and Number:
Japanese Patent JP2003506438
Kind Code:
A
Abstract:
Compounds of formula (II) are antibacterial agents wherein Q represents a radical of the formula: —N(OH)CH(═O) or the formula: —C(═O)NH(OH); R1 represents hydrogen, C1-C6 alkyl or C1-C6 alkyl substituted by one or more halogen atoms, or, except when Q is a radical of the formula: —N(OH)CH(═O), a hydroxy, C1-C6 alkoxy, C1-C6 alkenyloxy, amino, C1-C6 alkylamino, or di-(C1-C6 alkylamino group; R2 represents a substituted or unsubstituted C1-C6 alkyl, cycloalkyl(C1-C6 alkyl)- or aryl(C1-C6 alkyl)-group; and A represents a group of formula (IIA), or (IIB) wherein R4 represents the side chain of a natural or non-natural alpha amino acid, and R5 and R6 when taken together with the nitrogen atom to which they are attached form a saturated heterocyclic first ring of 5 to 7 atoms as specified in the description.
Inventors:
Pratt, Lisa, Marie
Keevey, Kenneth, Noel
Payne, Jills, Dennis
Meunier, Loren, Frank
Keevey, Kenneth, Noel
Payne, Jills, Dennis
Meunier, Loren, Frank
Application Number:
JP2001515301A
Publication Date:
February 18, 2003
Filing Date:
August 10, 2000
Export Citation:
Assignee:
British Biotech Pharmaceuticals Limited
International Classes:
A61K31/36; A61K31/445; A61K31/451; A61K31/4525; A61K31/454; A61K31/495; A61K31/496; A61K31/4965; A61K31/497; A61K31/506; A61K31/5377; A61P31/04; A61P43/00; C07D207/34; C07D209/08; C07D211/16; C07D211/22; C07D211/32; C07D211/40; C07D211/44; C07D211/46; C07D213/36; C07D213/38; C07D213/74; C07D213/81; C07D213/82; C07D217/06; C07D231/14; C07D239/28; C07D239/42; C07D239/557; C07D241/04; C07D241/24; C07D261/18; C07D277/20; C07D277/56; C07D285/06; C07D295/185; C07D295/192; C07D307/68; C07D317/58; C07D295/18; C07D317/68; C07D333/40; C07D401/04; C07D401/12; C07D405/14; C07D417/04; (IPC1-7): C07D211/16; A61K31/36; A61K31/445; A61K31/451; A61K31/4525; A61K31/454; A61K31/495; A61K31/496; A61K31/4965; A61K31/497; A61K31/506; A61K31/5377; A61P31/04; A61P43/00; C07D207/34; C07D209/08; C07D211/22; C07D211/32; C07D211/40; C07D211/44; C07D213/36; C07D213/81; C07D213/82; C07D217/06; C07D231/14; C07D239/28; C07D239/42; C07D239/557; C07D241/04; C07D241/24; C07D261/18; C07D277/56; C07D285/06; C07D295/18; C07D317/58; C07D333/40; C07D401/04; C07D401/12; C07D405/14; C07D417/04
Attorney, Agent or Firm:
Shintaro Nogawa