Title:
【発明の名称】抗ウイルス化合物および抗高血圧化合物
Document Type and Number:
Japanese Patent JPH06502845
Kind Code:
A
Abstract:
PCT No. PCT/US91/06250 Sec. 371 Date Mar. 1, 1993 Sec. 102(e) Date Mar. 1, 1993 PCT Filed Sep. 6, 1991 PCT Pub. No. WO92/04328 PCT Pub. Date Mar. 19, 1992.Compounds useful as antiviral agents against DNA-containing viruses, such as herpes group viruses, are disclosed. The compounds are are represented by compounds of Formula 1.0: (1.0) and their pharmaceutically acceptable salts and solvates. Pharmaceutical compositions containing compounds represented by Formula 1.0 and methods of treating a viral infection using compounds represented by Formula 1.0 are disclosed. Also disclosed are compounds useful as antihypertensive agents and methods of treating hypertension using such compounds. The antihypertensive agents are compounds represented by Formula 1.0 wherein R4 is selected from the group consisting of alkyl and aminoalkyl. Preferably R1 is H.
Inventors:
Afonso, Adriano
Wayne Stain, Jay
Gentles, Margaret Jevnik
Rosenblum, Stuart Barry
Wayne Stain, Jay
Gentles, Margaret Jevnik
Rosenblum, Stuart Barry
Application Number:
JP51456391A
Publication Date:
March 31, 1994
Filing Date:
September 06, 1991
Export Citation:
Assignee:
SCHERING CORPORATION
International Classes:
A61K31/11; A61K31/12; A61K31/13; A61K31/16; A61K31/18; A61K31/185; A61K31/22; A61K31/235; A61K31/365; A61K31/38; A61K31/382; A61K31/47; A61K31/695; A61P9/12; A61P31/12; C07C49/755; C07C49/757; C07C225/22; C07C235/82; C07C309/59; C07C311/16; C07C323/42; C07C323/62; C07C323/66; C07C323/67; C07D215/22; C07D215/56; C07D311/16; C07D311/18; C07D335/06; C07D401/06; C07D405/04; C07D405/12; C07D407/12; C07D409/12; C07D417/04; C07F7/18; C07F9/12; C07F9/38; C07F9/40; C07F9/60; C07F9/655; C07F9/6553; (IPC1-7): C07C49/755; A61K31/11; A61K31/12; A61K31/13; A61K31/16; A61K31/18; A61K31/185; A61K31/22; A61K31/235; A61K31/365; A61K31/38; A61K31/47; A61K31/695; C07C49/757; C07C225/22; C07C235/82; C07C309/59; C07C311/16; C07C323/42; C07C323/62; C07C323/66; C07C323/67; C07D215/22; C07D215/56; C07D311/18; C07D335/06; C07F9/12; C07F9/38; C07F9/40; C07F9/60; C07F9/655; C07F9/6553
Attorney, Agent or Firm:
Kyozo Yuasa (6 people outside)