Title:
【発明の名称】アポトーシス関連カルシウム結合タンパク質
Document Type and Number:
Japanese Patent JP2001507220
Kind Code:
A
Abstract:
The present invention provides a human apoptosis-related calcium-binding protein (HARC) and polynucleotides which identify and encode HARC. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HARC and a method for producing HARC. The invention also provides for agonists, antibodies, or antagonists specifically binding HARC, and their use, in the prevention and treatment of diseases associated with expression of HARC. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HARC for the treatment of diseases associated with the expression of HARC. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HARC.
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Inventors:
Hillman, Jennifer El
Gori, Surya Kay
Gori, Surya Kay
Application Number:
JP52688598A
Publication Date:
June 05, 2001
Filing Date:
December 08, 1997
Export Citation:
Assignee:
INCYTE PHARMACEUTICALS INC.
International Classes:
A61K45/00; A61P1/00; A61P1/16; A61P9/10; A61P13/12; A61P17/06; A61P19/02; A61P25/00; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P31/14; A61P31/20; A61P31/22; A61P35/00; A61P37/04; A61P37/06; G01N33/53; A61P43/00; C07K14/47; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/12; C12Q1/68; A61K38/00; (IPC1-7): C12N15/09; A61K45/00; A61P9/10; A61P13/12; A61P17/06; A61P19/02; A61P25/00; A61P27/02; A61P29/00; A61P31/14; A61P35/00; A61P37/04; A61P43/00; C07K14/47; C07K16/18; C12N1/15; C12N5/10; C12Q1/68; G01N33/53
Attorney, Agent or Firm:
Youichi Oshima