Title:
【発明の名称】ベンズヘテロ環式スルホン
Document Type and Number:
Japanese Patent JPH04504250
Kind Code:
A
Abstract:
The invention concerns novel, pharmaceutically useful, benzheterocyclyl sulphones of the formula I: I in which ring A may bear optional halogeno, (1-4C)alkyl or fluoro(1-4C)alkyl substituents; X is oxygen, or a group of the formula -S(O)n- or -NR1- in which n is zero, 1 or 2 and R1 is hydrogen, (1-4C)alkyl, (1-6C)alkanoyl, benzoyl or phenyl(1-4C)alkyl, the last two optionally substituted; Y is various linking groups defined hereinafter, such as ethylene or trimethylene; and in which the group -SO2CH2NO2 is located at position a, b or c in ring A; together with the non-toxic thereof. Other aspects of the invention include the production of the novel compounds by analogy processes and pharmaceutical compositions of the novel compounds for use in the treatment of diabetic complications.
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Inventors:
Britstein, Dave It Robert
Kotsk, Michael Thomas
Kotsk, Michael Thomas
Application Number:
JP50269490A
Publication Date:
July 30, 1992
Filing Date:
February 01, 1990
Export Citation:
Assignee:
Imperial Chemical Industries PLC
International Classes:
A61K31/34; A61K31/343; A61K31/38; A61K31/381; A61K31/382; A61K31/403; A61K31/404; A61K31/405; A61K31/47; A61P3/08; C07D209/08; C07D209/34; C07D333/54; C07D215/06; C07D215/08; C07D215/36; C07D307/79; C07D311/22; C07D311/58; C07D313/08; C07D335/06; (IPC1-7): A61K31/34; A61K31/38; A61K31/405; A61K31/47; C07D209/08; C07D209/34; C07D215/36; C07D307/79; C07D311/22; C07D311/58; C07D333/54; C07D335/06
Attorney, Agent or Firm:
Toshio Yano (1 outside)