Title:
【発明の名称】生物学的に活性なカルボン酸エステル類
Document Type and Number:
Japanese Patent JP2763894
Kind Code:
B2
Abstract:
The invention provides compounds of formulae XCH2-CHX-CHX-C(=O)-O-Z (I), CH3-CO-CH2-C(=O)-O-Z (II) and CH3-CH2-CO-C(=O)-O-Z (III), wherein X is H, or one X only may be OH; Z is -CHR-O-(O=)C-R min or and either R represents hydrogen, alkyl, aralkyl or aryl, and R min represents alkyl, aminoalkyl, amino(substituted alkyl), aralkyl, aryl, alkoxy, aralkoxy or aryloxy, provided that in (I) when X is H and R min is propyl, then R is alkyl which contains at least two carbon atoms, aralkyl and aryl, or R and R min together constitute a single bivalent radical whereby the compounds of formula (I) include an oxygen-containing heterocyclic ring; and R sec represents hydrogen, alkyl, aralkyl or aryl. The compounds of the above formulae are endowed with antitumor or immune response modulating effects.
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Inventors:
ABURAHAMU NUUDERUMAN
MACHICHIAFU SHAKURAI
ADA REFUAERI
MACHICHIAFU SHAKURAI
ADA REFUAERI
Application Number:
JP19198188A
Publication Date:
June 11, 1998
Filing Date:
July 30, 1988
Export Citation:
Assignee:
UNIV BAR ILAN (IL)
KUPAT HOLIM HEALTH INSURANCE (IL)
KUPAT HOLIM HEALTH INSURANCE (IL)
International Classes:
C07C271/16; A61K31/215; A61K31/22; A61K31/225; A61K31/335; A61K31/357; A61P35/00; A61P37/00; A61P37/02; A61P37/04; C07C67/00; C07C69/003; C07C69/28; C07C69/96; C07C227/00; C07C227/16; C07C227/18; C07C229/08; C07C229/36; C07C239/00; C07D307/83; C07D307/89; C07D317/34; C07D317/40; (IPC1-7): C07C69/28; A61K31/215
Domestic Patent References:
| JP50132123A | ||||
| JP63101348A | ||||
| JP4535297B1 |
Other References:
【文献】米国特許4012526(US,A)
【文献】米国特許3293220(US,A)
【文献】米国特許3293220(US,A)
Attorney, Agent or Firm:
Kazuo Shamoto (2 outside)