Title:
【発明の名称】血液細胞処理剤
Document Type and Number:
Japanese Patent JP2834514
Kind Code:
B2
Abstract:
PURPOSE:To obtain an atoxic and useful substance free from elution by immobilizing glucuronic acid to the surface of insoluble carrier by amide bond. CONSTITUTION:An aromatic vinyl-based copolymer including a homopolymer of styrene or alpha-methylstyrene is molded into a molded article such as a laboratory dish, bottle, film, fiber, hollow fiber, granule, etc. Aminomethyl group is introduced to the surface of the molded article to give a light transmitting insoluble carrier (A) having <=3 absorbance at 500-70nm wavelength in >=100mu thickness. Then the component A is immersed in a mixed solution of glucuronic acid and carbodiimide and immobilized to produce a treating agent (B) of blood cell. Optionally the component B is cultured while bringing the component B into contact with leukocyte to produce a cytokinin which is an interleukin such as interleukin-1 and a colony stimulating factor such as GM-CFS.
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Inventors:
TERAMOTO KAZUO
OGAWA TAKAYOSHI
NAKAMURA NORIKO
SUDO TETSUHISA
OGAWA TAKAYOSHI
NAKAMURA NORIKO
SUDO TETSUHISA
Application Number:
JP3137890A
Publication Date:
December 09, 1998
Filing Date:
February 14, 1990
Export Citation:
Assignee:
BAIO MATERIARU KENKYUSHO KK
International Classes:
C12M1/22; A61K35/14; A61K35/15; A61M5/14; A61M5/178; A61M25/00; C07H7/033; C12M1/24; C12N11/08; C12P21/00; C12R1/91; (IPC1-7): C12P21/00
Attorney, Agent or Firm:
Masahiko Sudo (1 outside)