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Title:
【発明の名称】カルシウムシトレートマレート組成物
Document Type and Number:
Japanese Patent JP3501800
Kind Code:
B2
Abstract:
A metastable complex of calcium, citrate and malate is disclosed. This material is highly bioavailable, and is soluble in both neutral and acid solutions. The salt is prepared by the reaction of calcium carbonate, calcium hydroxide or calcium oxide with citric and malic acids in aqueous solution. The reaction mixture is dried at a temperature of less than 100 DEG C, and the resultant solid is a metastable solid. The solid can be ground to reduce the particle size for easier tabletting or adding to foods and beverages. Preferred salts are neutral and acidic salts which can be expressed by molar ratios.

Inventors:
Fox, Mary Mora
Heckert, David Clinton
Larsen, Kennis Ray
Application Number:
JP51030591A
Publication Date:
March 02, 2004
Filing Date:
May 30, 1991
Export Citation:
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Assignee:
Tropicana Products Inc.
International Classes:
A61P1/02; A61P3/00; A61P3/14; A61P43/00; A61K31/19; C07C51/41; C07C59/245; C07C59/265; (IPC1-7): C07C59/265; A61K31/19; C07C51/41; C07C59/245
Domestic Patent References:
JP1156985A
JP1151515A
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)