Title:
【発明の名称】セファロスポリン化合物
Document Type and Number:
Japanese Patent JP2888638
Kind Code:
B2
Abstract:
PCT No. PCT/GB92/02231 Sec. 371 Date Jun. 1, 1994 Sec. 102(e) Date Jun. 1, 1994 PCT Filed Dec. 1, 1992 PCT Pub. No. WO93/11131 PCT Pub. Date Jun. 10, 1993 beta -lactam antibiotics of formula (I) or a salt thereof, wherein R1 is hydrogen, methoxy of formamido; R2 is an acyl group, in particular that of an antibacterially active cephalosporin; CO2R3 is a carboxy group or a carboxylate anion, or R3 is a readily removable carboxy protecting group (such as a pharmaceutically acceptable in vivo hydrolysable ester group); R4 represents up to four substituents selected from alkyl, alkenyl, alkynyl, alkoxy, hydroxy, halogen, amino, alkylamino, acylamino, dialkylamino, CO2R, CONR2, SO2NR2 (where R is hydrogen or C1-6 alkyl), aryl and heterocyclyl, which may be the same or different and wherein any R4 alkyl substituent is optionally substituted by any other R4 substituent; X is S, SO, SO2, O or CH2; Y is S, SO or SO2; and m is 1 or 2, useful in the treatment of bacterial infections in humans and animals. (I)
Inventors:
BAATON JOOJI
FUERU SUTEIIBUN KURISUTOFUAA MAATEIN
FUERU SUTEIIBUN KURISUTOFUAA MAATEIN
Application Number:
JP50996092A
Publication Date:
May 10, 1999
Filing Date:
December 01, 1992
Export Citation:
Assignee:
FUAIZAA INC
International Classes:
A61K31/545; A61K31/546; A61P31/04; C07D498/04; C07D501/00; C07D501/18; C07D501/20; C07D501/24; (IPC1-7): C07D501/20; A61K31/545
Domestic Patent References:
| JP4273882A | ||||
| JP6500788A |
Other References:
【文献】国際公開92/4353(WO,A1)
【文献】欧州公開477717(EP,A1)
【文献】欧州公開477717(EP,A1)
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)