Title:
【発明の名称】放射免疫療法用キレート化剤
Document Type and Number:
Japanese Patent JP2002528458
Kind Code:
A
Abstract:
The invention relates to compounds of formula (I): in which: n1, n2, n3 and n4, represent an integer from 1 to 5, R1, R2, R3 and R4, independently from each other, represent -COOH, -PO(OH)2, at least one of R1, R2, R3 or R4 represents a group (II), wherein n5 represents an integer from 1 to 5, R5 represents -COOH or -PO(OH)2, and Y represents H or a group -(CH2)n6-R6 in which n6 represents an integer from 1 to 5, and R6 represents -COOH or -PO(OH)2, R represents H, or a group carrying a function linked to molecules able to bind with epitopes at the surface of cells. The invention also relates to the processes of preparation of said compounds, and to their use in pharmaceutical compositions and in diagnosis methods.
Inventors:
Jestan, Jean-Francois
Ruth Warun, Antony
Favre-Schoev, Alain
Ruth Warun, Antony
Favre-Schoev, Alain
Application Number:
JP2000578321A
Publication Date:
September 03, 2002
Filing Date:
October 22, 1999
Export Citation:
Assignee:
INSERM(INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
International Classes:
A61K47/48; A61K51/00; A61K51/08; A61K51/10; A61P35/00; C07C229/16; G01N33/60; C07F9/38; C07K16/00; (IPC1-7): C07C229/16; A61K51/00; A61P35/00; C07F9/38; C07K16/00
Attorney, Agent or Firm:
Hajime Tsukuni (1 person outside)