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Title:
【発明の名称】化学修飾顆粒球コロニー刺激因子
Document Type and Number:
Japanese Patent JP2989002
Kind Code:
B2
Abstract:
A new chemically modified protein consists of human granulocyte colony stimulating factor (G-CSF) (aminoacid sequence of 174 units ( or 175 with N-terminal methionine) given in the patent) (expressed by host cells from a foreign DNA sequence) bound to polyethylene glycol either through the amino gps. of the aminoacid residues or through carboxyl gps.

Inventors:
Rika Ishikawa
Okada Yuji
Kakitani Makoto
Application Number:
JP50114490A
Publication Date:
December 13, 1999
Filing Date:
December 22, 1989
Export Citation:
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Assignee:
Kirin-Amjien Incorporated
International Classes:
A61K47/48; C07K14/535; C07K17/08; A61K38/00; (IPC1-7): C07K14/535; A61K31/00; A61K38/00; C12N15/09; C12P21/02
Domestic Patent References:
JP57192435A
JP6310800A
JP63126900A
JP6360938A
JP62289522A
JP62503171A
Attorney, Agent or Firm:
Yusuke Hiraki (1 person outside)