Title:
【発明の名称】コレステロール低下化合物及びそれらの製造方法
Document Type and Number:
Japanese Patent JPH06511250
Kind Code:
A
Abstract:
Disclosed are novel saponins containing 5-C-hydroxymethylhexose and a sterol or triterpene. These materials, when consumed by humans and animals, lower the cholesterol level in the blood. These compounds can be administered as pharmaceutical preparation to the diet, or incorporated into food compositions. The compositions are prepared by preparing and then reacting a fluoro or bromo hexaacylated 5-C-hydroxymethylhexose with a sterol. In a second method the hexaacylated 5-C-hydroxymethylhexose is reacted with a sterol in the presence of trimethylsilyl trifluoromethane sulfonate.
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Inventors:
Mother, adam whithle
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Dougie, Bruce Paul
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Dougie, Bruce Paul
Application Number:
JP50700993A
Publication Date:
December 15, 1994
Filing Date:
September 29, 1992
Export Citation:
Assignee:
THE PROCTER AND GAMBLE COMPANY
International Classes:
A61K31/7024; A61K31/704; A61P3/06; C07H13/04; C07J17/00; C07J71/00; (IPC1-7): C07H13/04; A61K31/705; C07J17/00
Attorney, Agent or Firm:
Kazuo Sato (3 others)