Title:
【発明の名称】シアリダーゼの発色基質とその製造法および使用法
Document Type and Number:
Japanese Patent JP2003522113
Kind Code:
A
Abstract:
The subject invention discloses materials and methods for the design, synthesis, and biochemical evaluation of chromogenic substrate compounds for sialidases of bacterial, viral, protozoa, and vertebrate (including humans) origin. In particular, this invention provides a novel class of effective compounds as chromogenic substrates of these sialidases which yield chromogenic products after reactions catalyzed by sialidases take place. Also provided are methods of making these substrate compounds, methods of diagnosis and prognosis of sialidase related diseases using these substrate compounds.
Inventors:
Johnson Stephanie.
Said Ashraf
Luo Min
Said Ashraf
Luo Min
Application Number:
JP2000578323A
Publication Date:
July 22, 2003
Filing Date:
October 27, 1998
Export Citation:
Assignee:
UBE Research Foundation
International Classes:
G01N33/68; C07H15/203; C07H15/26; C07H17/02; C07H17/075; C12N9/24; C12Q1/04; C12Q1/34; G01N21/78; (IPC1-7): C07H15/203; C07H15/26; C07H17/02; C07H17/075; C12N9/24; G01N21/78; G01N33/68
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| JPH0288594A | 1990-03-28 | |||
| JPH05505099A | 1993-08-05 | |||
| JPS54500072A | 1979-11-29 | |||
| JPH03175999A | 1991-07-31 | |||
| JPH0686684A | 1994-03-29 | |||
| JPH0246280A | 1990-02-15 | |||
| JPH0638784A | 1994-02-15 | |||
| JPH05339283A | 1993-12-21 | |||
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Foreign References:
| WO1991010744A1 | 1991-07-25 | |||
| WO1991009971A1 | 1991-07-11 | |||
| WO1991009975A1 | 1991-07-11 | |||
| US3950322A | 1976-04-13 | |||
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Attorney, Agent or Firm:
Shimizu Hatsushi (1 person outside)