Title:
【発明の名称】制御放出組成物
Document Type and Number:
Japanese Patent JP2927950
Kind Code:
B2
Abstract:
An article for controlled delivery of an active substance into an aqueous phase has a first layer containing an active substance, and a second layer of a crystalline polymer matrix and a non-ionic surface active agent, the second layer also containing the same or different active substance substantially homogeneously dispersed therein. The article enables release of a drug at a constant plateau level, followed by a pulse of drug after a predetermined time, thus making the composition of the invention especially suitable for use in, e.g., treatment of rheumatoid arthritis or related disorders with non-steroidal anti-inflammatory agents.
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Inventors:
BAARUUSHAROMU DANIERU
KINTOORAARUSEN TSUURU
KINTOORAARUSEN TSUURU
Application Number:
JP51388390A
Publication Date:
July 28, 1999
Filing Date:
September 21, 1990
Export Citation:
Assignee:
BUUKU MEDEITETSUKU AS
International Classes:
A61K9/00; A61K9/20; A61K9/22; A61K9/28; B82B1/00; (IPC1-7): A61K9/22; A61K9/28
Attorney, Agent or Firm:
Shintaro Nogawa