Title:
【発明の名称】環状ペプチド化合物およびそれらの誘導体
Document Type and Number:
Japanese Patent JPH11505208
Kind Code:
A
Abstract:
PCT No. PCT/JP96/00774 Sec. 371 Date Sep. 29, 1997 Sec. 102(e) Date Sep. 29, 1997 PCT Filed Mar. 26, 1996 PCT Pub. No. WO96/30399 PCT Pub. Date Oct. 3, 1996New peptide compounds of the formula: wherein R1 is alkyl or aralkyl, R2 is amino(lower)alkyl or protected amino(lower)alkyl, R3 is hydroxy, protected hydroxy, amino or protected amino, R4 is hydroxy, or R3 and R4 are linked together to form -Z- (in which -Z- is -O- or -NH-), and R5 is hydrogen or an amino protective group, R6 is hydroxy, or R5 and R6 are linked together to form bond, with proviso that when R3 is hydroxy, protected hydroxy, amino or protected amino and R4 is hydroxy, then R5 and R6 are linked together to form bond, and a pharmaceutically acceptable salt thereof, which is useful as a medicament.
Inventors:
Hashimoto Michizane
Shinji Shigematsu
Shoji Hashimoto
Shinji Shigematsu
Shoji Hashimoto
Application Number:
JP52916196A
Publication Date:
May 18, 1999
Filing Date:
March 26, 1996
Export Citation:
Assignee:
Fujisawa Pharmaceutical Co., Ltd.
International Classes:
A61P31/00; C07K1/02; C07K1/06; C07K1/12; C07K7/06; C07K7/08; C07K7/56; A61K38/00; C07K11/02; (IPC1-7): C07K7/08; A61K38/00; C07K1/02; C07K1/06; C07K1/12; C07K7/06; C07K11/02