Title:
【発明の名称】サイトカイン合成抑制性因子、そのアンタゴニストおよびそれらの使用方法
Document Type and Number:
Japanese Patent JP2813063
Kind Code:
B2
Abstract:
Mammalian genes and proteins, designated cytokine synthesis inhibitory factors (CSIFs), are provided which are capable of inhibiting the synthesis of cytokines associated with delayed type hypersensitivity responses, and which, together with antagonists, are useful in treating diseases associated with cytokine imbalances, such as leishmaniasis and other parasitic infections, and certain immune disorders including MHC associated autoimmune diseases caused by excessive production of interferon- gamma .
Inventors:
Mossman, Timothy Earl
Moore, Kevin W
Bond, Martha W.
Vila, Paul Jay M
Moore, Kevin W
Bond, Martha W.
Vila, Paul Jay M
Application Number:
JP51072590A
Publication Date:
October 22, 1998
Filing Date:
June 28, 1990
Export Citation:
Assignee:
SCHERING CORPORATION
International Classes:
A61K38/00; A61K39/395; A61P37/00; C07K14/00; C07K14/435; C07K14/54; C07K16/00; C12N15/09; C07K16/24; C12N5/10; C12N15/02; C12N15/24; C12P21/00; C12P21/08; C12R1/91; (IPC1-7): C07K14/435; A61K38/00; A61K39/395; C12N15/09; C12P21/00; C12P21/08
Domestic Patent References:
| JP61219395A |
Other References:
Ｊｏｕｒｎａｌ ｏｆ Ｅｘｐｅｒｉｍｅｎｔａｌ Ｍｅｄｉｃｉｎｅ，Ｖｏｌ．１６６，Ｎｏ２（１９８７）ｐ．５７１−５７６
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)