Title:
【発明の名称】トランスジェニック植物における免疫原性B型肝炎表面抗原の発現
Document Type and Number:
Japanese Patent JP2003512812
Kind Code:
A
Abstract:
Plant expression vectors comprising at least two expression cassettes are provided which function to reduce transcriptional silencing of polynucleotide expression. Further, novel plant expression vectors for expression of immunogenic polypeptides, including HBsAg, are provided. The plant expression vectors can be used to produce immunogenic polypeptides, including HBsAg, in edible plant tissues. The edible plant tissues can be used to elicit an immune response in humans and animals when the plant tissues are consumed.
Inventors:
Mason, Hues.
Tanavara, Yasmine
Arunzen, Charles Joel
Richter, Elizabeth
Tanavara, Yasmine
Arunzen, Charles Joel
Richter, Elizabeth
Application Number:
JP2000589666A
Publication Date:
April 08, 2003
Filing Date:
December 23, 1999
Export Citation:
Assignee:
Boyce Thompson Institute for Plant Research
Health Research Institute
Health Research Institute
International Classes:
A01H5/00; A61K36/23; A61K36/81; A61K39/00; A61P31/12; C07K14/02; C12N1/21; C12N5/10; C12N15/09; C12N15/51; C12N15/82; C12R1/19; C12R1/91; (IPC1-7): C12N15/09; A01H5/00; A61K35/78; A61K39/00; A61P31/12; C12N1/21; C12N5/10
Attorney, Agent or Firm:
Hidekazu Miyoshi (1 outside)