Title:
【発明の名称】ハロ-フィルスマイヤー試薬を使用するハロゲン化
Document Type and Number:
Japanese Patent JPH07505138
Kind Code:
A
Abstract:
The invention provides an improved process for the preparation of a halogenated steroidal diene. The process involves the simultaneous transformation of the steroidal 3-one to 3-halo and 17-carboxylic acid to 17-carboxamide in a single reaction without the isolation of an intermediate. The process takes place by reacting the steroidal starting material with a halogen-Vilsmeier reagent.
Inventors:
Bane, Neil Howard
Klein, Donald Nataniel
Mew Shaw, Richard Eric
Owings, franklin
Klein, Donald Nataniel
Mew Shaw, Richard Eric
Owings, franklin
Application Number:
JP51254293A
Publication Date:
June 08, 1995
Filing Date:
January 06, 1993
Export Citation:
Assignee:
SMITHKLINE BEECHAM CORPORATION
International Classes:
C07J3/00; C07J9/00; C07J41/00; C07J43/00; C07J75/00; C07C235/00; (IPC1-7): C07J75/00; C07J41/00; C07J43/00
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)