Title:
【発明の名称】複素環アミジノ尿素
Document Type and Number:
Japanese Patent JPS58500716
Kind Code:
A
Abstract:
This invention relates to heterocyclic amidinoureas and heterocyclic amidinothioureas of the formulawherein:X is OorS;R1 is a thienyl group, in particular a 2-thiophene or a 3-thiophene group,or an S-oxide thereof;R2, R3 and R4 are hydrogen or lower alkyl;R6 and R6 are hydrogen, alkyl, cycloalkyl, aralkyl, alkenyl, aryl, alkoxy or a heterocyclic group, or R5 and R6 together with the nitrogen to which they are attached form a 3 to 7 atom ring which may include 0 to 2 additional hetero atoms of N, 0 or S; or a non-toxic acid addition salt thereof.The compounds of the invention exhibit pharmacological activity and may be incorporated into a pharmacological preparation useful for producing cardiovascular, gastrointestinal and antiparasitic action.
Inventors:
Stat william lion
Zimmer-Man Haly Call
Douglas Giyo-The Henri-
Zimmer-Man Haly Call
Douglas Giyo-The Henri-
Application Number:
JP50182482A
Publication Date:
May 06, 1983
Filing Date:
May 12, 1982
Export Citation:
Assignee:
Loula-Internacional (Overseas) Inco-Pole-Ted
International Classes:
C07D207/00; C07D207/14; C07D207/22; C07D207/34; C07D207/46; C07D207/50; C07D209/08; C07D209/40; C07D213/00; C07D213/75; C07D213/80; C07D213/85; C07D213/89; C07D215/38; C07D215/42; C07D215/58; C07D217/08; C07D217/22; C07D233/88; C07D239/42; C07D261/14; C07D263/48; C07D265/30; C07D275/03; C07D295/28; C07D307/22; C07D307/66; C07D333/36; C07D333/38; C07D498/00; C07D498/04; C07D521/00; C07D275/02; (IPC1-7): C07D498/04; C07D333/36; C07D213/89; C07D213/75; C07D207/50; A61K31/44; A61K31/40; A61K31/38
Attorney, Agent or Firm:
Minoru Nakamura