【発明の名称】複素環式キレート化剤

Title:

【発明の名称】複素環式キレート化剤

Document Type and Number:

Japanese Patent JP2953670

Kind Code:

B2

Abstract:

Heterocyclic chelating agents and salts thereof of formula I: (I) wherein X represents a bond, O or S, or a group CHR1 or NR3, each R1 represents H, a group OR3 or NR3R3, or an alkyl or alkoxyalkyl group optionally substituted by a hydroxyl group or by a group NR3R3 or CON3R3; each R2 represents H, or an alkyl or alkoxy group optionally substituted by a hydroxyl or aloxy group; each R3 represents H, an optionally hydroxylated alkyl group or a group CH2Y; Y represents a group COZ, CON(OH)R4, POZ2 or SO2Z; Z represents a group OR4, NR4R4 or where each R11 is H, a hydroxyl group or an optionally hydroxylated alkyl group, s is 0, 1 or 2, and W is CHR11, NR11 or an oxygen atom; and each R4 represents H, or an optionally mono- or poly-hydroxylated alkyl, alkoxyalkyl or polyalkoxyalkyl group; with the provisos that where s is O then W is CHR11 and that where X represents a bond or CHR1, at least one group R1 or R2 represents other than H or an unsubstituted alkyl group. A process for preparing these agents and methods of heavy metal detoxification using these agents are alo described.

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Inventors:

ARUMEN TORUSUTEN
BERUGU ARUNE
DEYUGUSUTAADO HARARUDO
KURAAUENESU YOO
KURAEUTORUSUTO KURAEUSU DEIITERU
RONGUEEDO HOORU

Application Number:

JP50217190A

Publication Date:

September 27, 1999

Filing Date:

January 15, 1990

Export Citation:

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Assignee:

NIKOMETSUDO AS

International Classes:

A61K47/48; A61K49/00; A61K49/04; A61K49/06; A61K51/00; A61K51/04; C07D207/14; C07D211/42; C07D211/46; C07D211/56; C07D241/04; C07D241/20; C07D265/30; C07D265/32; C07D279/12; C07F3/00; C07F5/00; C07F9/94; C07F13/00; (IPC1-7): C07D207/14; A61K49/00; A61K49/04; A61K51/00; C07D211/42; C07D211/46; C07D241/20; C07D265/30; C07D265/32; C07D279/12

Domestic Patent References:

JP635077A

Attorney, Agent or Firm:

Chika Takagi (2 outside)

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