Title:
【発明の名称】複素環式化合物およびその製造法
Document Type and Number:
Japanese Patent JP3011955
Kind Code:
B2
Abstract:
New heterocyclic compounds of formula I In which Het means one of following groups; wherein R11, R13 and R14 mean independently hydrogen, hydroxymethyl or lower alkyl group, Z means S, O or NH; A means valency bond, -CH=CH-, or -CH2-CH2- group; R1 and R2 independently mean nitro, cyano, halogen, amino, carboxamido, aryl, aroyl, pyridyl, alkoxycarbonyl, acyl or one of following groups; wherein R6 means hydrogen or lower alkyl group, R8 means lower alkyl, R7 means cyano or COOR10, wherein R10 means hydrogen or lower alkyl or R1 and R2 together form a susbtituted or unsubstituted 5 or 6 membered ring which may contain 1 or 2 heteroatom N; R3, R4, and R5 mean independently hydrogen, hydroxy or lower alkyl group; Y means N or CH. The compounds may be used in the treatment of congestive heart failure.
Inventors:
Hemo Orabi High Color
Erki Yuhani Honkanen
Kari Kalebi Lenberg
Pliers Tapio Nore
Yarmo Johan Pistinen
Anne Maria Luilo
Aino Kirikki Pippuri
Erki Yuhani Honkanen
Kari Kalebi Lenberg
Pliers Tapio Nore
Yarmo Johan Pistinen
Anne Maria Luilo
Aino Kirikki Pippuri
Application Number:
JP3133990A
Publication Date:
February 21, 2000
Filing Date:
February 09, 1990
Export Citation:
Assignee:
Orion-Yuhichume Oyu
International Classes:
A61K31/50; A61K31/501; A61K31/502; A61K31/53; A61K31/535; A61K31/54; A61P9/04; A61P9/08; A61P9/12; C07D237/04; C07D237/14; C07D237/32; C07D253/07; C07D273/04; C07D285/16; C07D285/18; C07D253/06; C07D401/12; C07D403/12; C07D413/12; C07D417/12; (IPC1-7): C07D237/04; A61P9/08; A61P9/04; A61P9/12; A61K31/50; A61K31/502; A61K31/53; A61K31/535; A61K31/54; C07D237/14; C07D237/32; C07D253/06; C07D273/04; C07D285/16; C07D401/12; C07D403/12
Domestic Patent References:
| JP63203667A | ||||
| JP62192367A | ||||
| JP6281314A | ||||
| JP57109771A |
Attorney, Agent or Firm:
Sota Asahina (2 outside)