Title:
【発明の名称】ヘテロ環化合物
Document Type and Number:
Japanese Patent JP3018442
Kind Code:
B2
Abstract:
Compounds of the general formula (I) in which:- R1 represents a hydroxyl protecting group; and R2 represents a hydrogen or halogen atom, an azido group, a C1-3 alkyl group, a group (CH2)mOR3 wherein m is zero or one and R3 represents a hydrogen atom or a hydroxyl protecting group, an azidoethoxy group, a protected hydroxyethoxy group or a group XR4 in which X is an oxygen atom or the group S(O)n in which n is zero, 1 or 2 and R4 represents a C1-5alkyl, C3-7 cycloalkyl or phenyl group or when X is oxygen or sulphur then R4 may also represent the group AlkNR5R6 in which Alk represents a C2-6 straight or branched alkylene chain and R5 and R6 independently represent a hydrogen atom or C1-4alkyl group or R5 and R6 together with the nitrogen atom to which they are attached form a pyrrolidino or piperidino ring or the group NR5R6 represents a protected amino group, or R2 represents the group (CH2)mNR7R8 in which m is zero or 1 and R7 and R8 independently represent a hydrogen atom or a C1-4alkyl group or NR7R8 represents a protected amino group, or R2 and the carbon atom to which it is attached represent a keto group or a ketal derivative thereof; and acid addition salts of such compounds containing basic centres.
Inventors:
Bruno Tambrini
Arcide Perboni
Teino Roshi
Daniele Donatoy
Daniele Andreottei
Giovanni Gaviiragi
Stefano Bionday
Claudio Bismara
Arcide Perboni
Teino Roshi
Daniele Donatoy
Daniele Andreottei
Giovanni Gaviiragi
Stefano Bionday
Claudio Bismara
Application Number:
JP23597690A
Publication Date:
March 13, 2000
Filing Date:
September 07, 1990
Export Citation:
Assignee:
Glaxo Societa Pell Atsuioni
International Classes:
C07D487/04; A61K31/395; A61K31/397; A61K31/40; A61K31/407; A61P31/04; C07C45/71; C07C49/753; C07D205/08; C07D477/00; C07D487/00; C07F7/18; A61K; C07D; C07F; (IPC1-7): C07D205/08
Attorney, Agent or Firm:
Chika Takagi (2 outside)