Title:
【発明の名称】複素環式エステルおよびアミド
Document Type and Number:
Japanese Patent JP2001502668
Kind Code:
A
Abstract:
This invention relates to neurotrophic low molecular weight, small molecule heterocyclic esters and amides having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
Inventors:
Li, Jae
Hamilton, Gregory, Es.
Hamilton, Gregory, Es.
Application Number:
JP51563898A
Publication Date:
February 27, 2001
Filing Date:
August 20, 1997
Export Citation:
Assignee:
Guildford Pharmaceuticals, Inc.
International Classes:
A61K31/41; A61K31/4164; A61K31/426; A61K31/454; A61K31/535; A61K31/54; A61P25/00; A61P25/16; A61P25/28; C07D233/02; C07D241/04; C07D263/02; C07D265/28; C07D265/30; C07D261/02; C07D267/02; C07D277/06; C07D279/12; C07D417/12; (IPC1-7): C07D233/02; A61K31/4164; A61K31/426; A61K31/454; A61K31/535; A61K31/54; A61P25/00; A61P25/16; A61P25/28; C07D265/30; C07D277/06; C07D279/12; C07D417/12
Attorney, Agent or Firm:
Nobuo Kaida (1 person outside)