Title:
【発明の名称】眼圧降下脂質
Document Type and Number:
Japanese Patent JP2003523976
Kind Code:
A
Abstract:
Compounds of Formula 1, where the symbols are as defined in the specification, are useful as ocular hypotensive agents but do not exert their activity through the FP prostaglandin receptor.In particular the compound PGF2alpha 1-ethanolamide, having the formulawas discovered to be present in mammalian tissue as a naturally occurring substance, was synthesized in a substantially pure form and was found to be effective for lowering intraocular pressure in the mammalian eye, but not acting through the FP receptor through which many ocular hypotensive prostaglandins act.
Inventors:
David F Woodward
Helen H. Usansky
Steven W Andrews
Robert M. Burke
June Chen
Ahim Ha Pa Klaus
Cherklee Madou
Helen H. Usansky
Steven W Andrews
Robert M. Burke
June Chen
Ahim Ha Pa Klaus
Cherklee Madou
Application Number:
JP2001558417A
Publication Date:
August 12, 2003
Filing Date:
February 05, 2001
Export Citation:
Assignee:
ALLERGAN,INCORPORATED
International Classes:
A61K9/00; A61P27/02; A61P27/06; A61K31/5575; C07C405/00; (IPC1-7): C07C405/00; A61K31/5575; A61P27/02
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)