NEW MATERIAL:A compound(salt) shown by the formula I , whose disodium salt having the following physical and chemical properties. Electrophoresis mobility of filter paper: 2.3(mobility of epithienamycin A is 1.0). 13C Nuclear magnetic resonance: δppm 21.7q, 3.24t, 55.0d, 60,4d, 64,4d, 127.7s, 139.8s, 169.0s, and 179.4s. 1H Nuclear magnetic resonance: δppm(J=Hz)0.72d(6.0),2.36d-d(16.5, 11.0), 2.59d-d (16.5, 9.0), 3,01d-d(10.0, 5.5), 3,63q-d(6.0, 10.0), and 3.78m. Infrared absorption spectrum: μKBrmaxcm-1 3435, 1755, 1615, 1395, 1220W1200, 1105, 1066, and 1039. Ultraviolet spectrum shown by the formula II.
USE: An antibacterial agent.
PROCESS: A bacterium (FERM-P 5964) belonging to the genus Streptomyces, capable of producing PA-41746-D, is inoculated into a medium, and a product is separated and collected to give a compound shown by the formula.
KONDOU EIJI
MATSUMOTO KOUICHI
TSUJI NAOKI
