Title:
【発明の名称】ペネムの製造方法
Document Type and Number:
Japanese Patent JP2688053
Kind Code:
B2
Abstract:
Compounds of the formula I : wherein R1 represents a hydroxy protecting group and R2 represents a carboxy protecting group, useful as intermediates for the preparation of penem antibiotics, are prepared by hydrolysing a compound of the formula II : wherein R1 and R2 are as defined above and R represents an alkyl, alkenyl or phenylalkyl group having from 1 to 18 carbon atoms, by means of an enzyme capable of se lectively hydrolysing the ester group of the 2-substituent thereof. d
Inventors:
Maria Altamura
Pietro Chistay
Franco Francaranch
Maruello Marchi
Marco Foua
Stefano Cambiagi
Franco Grat Mazina
Pietro Chistay
Franco Francaranch
Maruello Marchi
Marco Foua
Stefano Cambiagi
Franco Grat Mazina
Application Number:
JP25702887A
Publication Date:
December 08, 1997
Filing Date:
October 12, 1987
Export Citation:
Assignee:
Pharmacia e Upjohn Etssey Pear
International Classes:
C07D499/00; C07D499/04; C07D499/861; C07D499/88; C12P37/00; C07F7/18; (IPC1-7): C12P37/00
Attorney, Agent or Firm:
Yoshio Kawaguchi (3 outside)