Title:
【発明の名称】ペネム類の製造方法
Document Type and Number:
Japanese Patent JP2688065
Kind Code:
B2
Abstract:
Compounds of the formula I: wherein R is a carboxy group or a carboxylate anion, R2 represents a hydroxy protecting group or hydrogen atom, R1 represents one of certain defined organic groups, useful as antibiotics, are prepared by hydrolysing a compound of formula II: wherein R3 represents a hydrogen atom or a C1-6 alkyl group and R4 is hydrogen atom or a C1-18 alkyl, alkenyl, phenyl, phenylalkyl group, by means of an enzyme capable of selectively hydrolysing the ester group at 3-position.
Inventors:
Maria Altamura
Franco Francaranch
Maruti Etsuro Marchi
Franco Francaranch
Maruti Etsuro Marchi
Application Number:
JP16665188A
Publication Date:
December 08, 1997
Filing Date:
July 04, 1988
Export Citation:
Assignee:
Pharmacia e Upjohn Etssey Pear
International Classes:
C07D499/04; C07D499/08; C07D499/897; C07D499/88; C12P17/18; C12P37/00; (IPC1-7): C12P37/00
Attorney, Agent or Firm:
Yoshio Kawaguchi (3 outside)