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Title:
【発明の名称】新規な4―置換アントラサイクリノンおよびアントラサイクリン配糖体、並びにその製造方法
Document Type and Number:
Japanese Patent JPH04501414
Kind Code:
A
Abstract:
4-substituted anthracyclinones of formula (I): wherein R represents a straight or branched alkyl, alkenyl or alkynyl group of up to 16 carbon atoms optionally substituted by (a) an aryl group which is unsubstituted or substituted by an inert group such as an alkyl, alkoxy or nitro group; (b) an alkoxy group; (c) a trialkylsilyl group, (d) an ester group or (e) an amido group, are intermediates in the preparation of antitumor anthracycline glycosides of formula (IX): wherein R is as defined above and R1 is a hydrogen atom or a hydroxy group, and pharmaceutically acceptable salts thereof.

Inventors:
Cabri, Bartel
De Bernardinis, Sylvia
Franca Ranch, Franco
Penco, Sergiyo
Application Number:
JP51135989A
Publication Date:
March 12, 1992
Filing Date:
October 24, 1989
Export Citation:
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Assignee:
Faria Talia Carlo Erba Etsuse Elle Elle
International Classes:
A61K31/70; A61K31/7028; A61K31/7034; A61K31/704; A61P31/04; B01J31/22; C07B61/00; C07C46/00; C07C50/38; C07C67/343; C07C69/95; C07F7/08; C07H15/252; (IPC1-7): A61K31/70; B01J31/22; C07B61/00; C07C46/00; C07C50/38; C07C67/343; C07C69/95; C07F7/08; C07H15/252
Attorney, Agent or Firm:
Yoshio Kawaguchi (4 outside)



 
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