Title:
【発明の名称】新規磁気共鳴法造影剤
Document Type and Number:
Japanese Patent JP3040462
Kind Code:
B2
Abstract:
Novel magnetic resonance imaging agents comprise complexes of paramagnetic ions with hydrazide derivatives of polyaminocarboxylic acid chelating agents. These novel imaging agents are characterized by excellent NMR image-contrasting properties and by high solubilities in physiological solutions. A novel method of performing an NMR diagnostic procedure involves administering to a warm-blooded animal an effective amount of a complex as described above and then exposing the warm-blooded animal to an NMR imaging procedure, thereby imaging at least a portion of the body of the warm-blooded animal.
Inventors:
Rajagopalan, Ragaban
Application Number:
JP50811590A
Publication Date:
May 15, 2000
Filing Date:
March 12, 1990
Export Citation:
Assignee:
Mallinckrodt INC.
International Classes:
A61K49/00; A61K49/06; C07C243/34; C07D211/98; C07D295/22; (IPC1-7): C07C243/34; A61K49/00; C07D211/98; C07D295/22
Domestic Patent References:
| JP4832822A |
Other References:
【文献】米国特許3787482(US,A)
Attorney, Agent or Firm:
Hiroaki Tazawa (2 outside)