Title:
【発明の名称】フェニルヘテロアルキルアミン誘導体の新規なる使用
Document Type and Number:
Japanese Patent JP2003523995
Kind Code:
A
Abstract:
There is disclosed the use of a compound of formula (I), wherein R1, R2, X, Y, V, W and Z are as defined in the specification, and pharmaceutically acceptable salts, enantiomers or racemates thereof, in the manufacture of a medicament, for the treatment or prophylaxis of diseases or conditions in which inhibition of nitric oxide synthase activity is beneficial. Certain novel compounds of formula (Ia) and pharmaceutically acceptable salts thereof, and enantiomers and racemates thereof are disclosed; together with processes for their preparation, compositions containing them and their use in therapy. The compounds of formulae (I) and (Ia) are inhibitors of the enzyme nitric oxide synthase and are thereby particularly useful in the treatment or prohylaxis of inflammatory disease
Inventors:
David Cheshire
Steven Connolly
David Cox
Ian Millichip
Steven Connolly
David Cox
Ian Millichip
Application Number:
JP2001561730A
Publication Date:
August 12, 2003
Filing Date:
February 20, 2001
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
A61K31/137; A61K31/145; A61K31/275; A61K31/277; A61K31/365; A61K31/415; A61K31/421; A61K31/426; A61K31/5375; A61K31/695; A61K45/00; A61P1/00; A61P1/02; A61P1/04; A61P1/06; A61P1/18; A61P3/10; A61P9/02; A61P9/10; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P19/06; A61P25/02; A61P25/04; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/28; A61P25/30; A61P27/06; A61P29/00; A61P31/04; A61P35/00; A61P37/02; A61P43/00; C07C211/48; C07C211/52; C07C253/30; C07C255/58; C07C315/02; C07C317/28; C07C319/14; C07C323/29; C07C323/62; C07D263/32; C07D295/12; C07D277/28; C07D295/125; (IPC1-7): A61K31/145; A61K31/137; A61K31/275; A61K31/365; A61K31/415; A61K31/421; A61K31/426; A61K31/5375; A61K45/00; A61P1/00; A61P1/02; A61P1/04; A61P1/06; A61P1/18; A61P3/10; A61P9/02; A61P9/10; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P19/06; A61P25/02; A61P25/04; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/28; A61P25/30; A61P27/06; A61P29/00; A61P31/04; A61P35/00; A61P37/02; A61P43/00; C07C211/52; C07C253/30; C07C255/58; C07C315/02; C07C317/28; C07C319/14; C07C323/29; C07C323/62; C07D263/32; C07D277/28; C07D295/12
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)