Title:
【発明の名称】新規なリポソームベクター複合体および遺伝子療法でのそれらの使用
Document Type and Number:
Japanese Patent JP2003501373
Kind Code:
A
Abstract:
The invention relates to a novel liposomal vector complex, containing the following components: a) a nucleic acid sequence of any length; b) a cationic support which condenses the component a) and is lysosomolytic and/or lysosomotropic; c) lipids and phospholipids which form a liposome; d) optionally a ligand which has a connecting point for a target cell; and e) optionally a fusogenic substance which can replace the lysosomolytic and/or lysosomotropic functions of component b). If a fusogenic substance (e) is present, the cationic support (b) need not be lysosomolytic and/or lysosomotropic. The invention also relates to the production and use of said complex.
Inventors:
Sabine Brussels Baja
Christina Muller
Alfreet fur
Christina Muller
Alfreet fur
Application Number:
JP2001501183A
Publication Date:
January 14, 2003
Filing Date:
May 23, 2000
Export Citation:
Assignee:
Aventis Pharma Deutsche Land Gesellschaft Mitt Beschlenktel Haftung
International Classes:
A61K9/12; A61K9/127; A61K31/7088; A61K47/24; A61K47/34; A61K47/42; A61K47/48; A61K48/00; A61P35/00; C12N15/87; (IPC1-7): A61K48/00; A61K9/12; A61K9/127; A61K31/7088; A61K47/24; A61K47/34; A61K47/42
Attorney, Agent or Firm:
Chika Takagi (2 outside)