Title:
【発明の名称】新規ステロイドジオール,それらを含む医薬組成物、およびそれらの調製方法
Document Type and Number:
Japanese Patent JPH06104679
Kind Code:
B2
Abstract:
The invention relates to DELTA <1><4>-16 alpha ,17-dihydroxypregnane derivatives of general formula (I), wherein A represents a hydrogen atom, or hydroxyl or trifluoroacetoxy group; X represents a hydrogen or halogen atom with the proviso that if A is a hydrogen atom, X is also a hydrogen atom; R represents a hydrogen atom, a benzoyl or C1-8 alkanoyl group; and --- represents a single or double bond between the two adjacent carbon atoms, as well as pharmaceutical compositions containing these compounds and a process for their preparation. The compounds of general formula (I) possess valuable antiinflammatory effects and thus may be used as active ingredients in antiinflammatory pharmaceutical compositions. They may also be useful in the preparation of other therapeutically useful steroid derivatives.
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Inventors:
Chaba Mornar
Giorgio Hyoche
Lars Roe Sporgne
Youth tots
Earl Pad Killari
Anna Boole
Janos Chorgey
Christina Sikeli
Lilla Folgerchu
Giorgi Fekete
Bruchu Helleny
Thunder holly
Youssef Seonyug
Giorgio Hyoche
Lars Roe Sporgne
Youth tots
Earl Pad Killari
Anna Boole
Janos Chorgey
Christina Sikeli
Lilla Folgerchu
Giorgi Fekete
Bruchu Helleny
Thunder holly
Youssef Seonyug
Application Number:
JP5516290A
Publication Date:
December 21, 1994
Filing Date:
March 08, 1990
Export Citation:
Assignee:
Richter Gedeon Bejeseti Jarl Earl.
International Classes:
A61K31/57; A61P29/00; C07J5/00; C07J13/00; (IPC1-7): C07J5/00; A61K31/57
Domestic Patent References:
| JP535149A | ||||
| JP2504511A | ||||
| JP5874700A | ||||
| JP57122100A |
Attorney, Agent or Firm:
Aoki Akira (3 outside)