Title:
【発明の名称】オキサチオランと、その製造方法と、それを含む医薬組成物
Document Type and Number:
Japanese Patent JPH09502453
Kind Code:
A
Abstract:
PCT No. PCT/FR95/00683 Sec. 371 Date Jan. 19, 1996 Sec. 102(e) Date Jan. 19, 1996 PCT Filed May 24, 1995 PCT Pub. No. WO95/32200 PCT Pub. Date Nov. 30, 1995The present invention pertains to the field of organic chemistry, and particularly therapeutic chemistry. The invention provides cis-form 5-(cytosinyl-1) 1,3-oxathiolanes of general formula (I), wherein R is an acyl or aralkoyl radical, derivatized from a nitrogen monocyclic or bicyclic heterocycle, and the hydroxymethyl group in position 2 is in cis position in relation to the plane defined by positions 2 and 5. The compounds of general formula (I) are useful as active ingredients in pharmaceutical compositions, particularly with antiviral activity.
Inventors:
Charve-Foley, Anne-Sophie
Campro, Michelle
Kuro, Jean-Louis
Campro, Michelle
Kuro, Jean-Louis
Application Number:
JP53010895A
Publication Date:
March 11, 1997
Filing Date:
May 24, 1995
Export Citation:
Assignee:
Labor Toile Rafal
International Classes:
A61K31/44; A61K31/465; A61K31/47; A61K31/506; A61K31/513; A61P31/12; A61P37/04; C07D211/00; C07D239/00; C07D327/00; C07D411/14; C07F7/18; (IPC1-7): C07D411/14; A61K31/44; A61K31/465; A61K31/47
Attorney, Agent or Firm:
Takashi Koshiba