Title:
【発明の名称】フェニル置換4-アザステロイドフルオロ誘導体
Document Type and Number:
Japanese Patent JPH10509188
Kind Code:
A
Abstract:
Compounds of formula (I), wherein: the symbol +E,uns ----+EE represents a single or a double bond; R is a hydrogen atom or a C1-C4 alkyl group; Rf and R'f, each independently, are C1-C4 alkyl groups substituted by one or more fluorine atoms; and R1 and R2, each independently, are selected from: a hydrogen atom; a phenyl group; a C1-C4 alkyl group unsubstituted or substituted by one or more fluorine atoms; a halogen atom; a cyano (CN) group; a group OR4, wherein R4 is a hydrogen atom or a C1-C4 alkyl group; a group SR5, wherein R5 is a hydrogen atom or a C1-C4 alkyl group; and a group COR6, wherein R6 is a group OR4 in which R4 is as defined above or a C1-C4 alkyl group unsubstituted or substituted by one or more fluorine atoms. They are useful as testosterone 5a-reductase inhibitors.
Inventors:
Pants Eri, Achille
Nesie, multi-era
Day Sale, Enrico
Nesie, multi-era
Day Sale, Enrico
Application Number:
JP51159397A
Publication Date:
September 08, 1998
Filing Date:
August 09, 1996
Export Citation:
Assignee:
Farmacia e Appzyon Esset Pear
International Classes:
A61P43/00; C07J73/00; A61K31/58; (IPC1-7): C07J73/00; A61K31/58
Attorney, Agent or Firm:
Yoshio Kawaguchi (3 outside)