Title:
【発明の名称】フェニル-アルキル-イミダゾール型のH3レセプターリガンド
Document Type and Number:
Japanese Patent JP2001522835
Kind Code:
A
Abstract:
Disclosed are novel phenyl-alkyl-imidazoles of formula (I) or pharmaceutically acceptable salts or solvates thereof, wherein A and R, are as defined in the specification. Also disclosed are methods of treating allergy, inflammation, hypotension, glaucoma, sleeping disorders, states of hyper and hypo motility of the gastrointestinal tract, hypo and hyperactivity of the central nervous system, Alzheimer's, schizophrenia, obesity and migraines, comprising administering an effective amount of a compound of formula (I) (or a salt or solvate thereof) to a patient in need of such treatment. Also disclosed are methods for treatment of upper airway allergic responses comprising administering a compound, or salt or solvate thereof, of formula (I) in combination or admixture with a histamine H1 receptor antagonist.
Inventors:
Aslanian, Robert G.
McCormick, Kevin Dee.
Mutahi, Mwangiwa
McCormick, Kevin Dee.
Mutahi, Mwangiwa
Application Number:
JP2000520419A
Publication Date:
November 20, 2001
Filing Date:
November 05, 1998
Export Citation:
Assignee:
Schering Corporation
International Classes:
A61K31/4164; A61K31/445; A61K31/495; A61P1/04; A61P3/04; A61P9/00; A61P9/02; A61P25/00; A61P25/06; A61P25/18; A61P25/20; A61P25/28; A61P27/06; A61P29/00; A61P37/08; C07D233/54; C07D233/64; (IPC1-7): C07D233/64; A61K31/4164; A61P1/04; A61P3/04; A61P9/00; A61P9/02; A61P25/00; A61P25/06; A61P25/18; A61P25/20; A61P25/28; A61P27/06; A61P29/00; A61P37/08
Attorney, Agent or Firm:
Shusaku Yamamoto