Title:
【発明の名称】ナノカプセルの形態を有する,シクロデキストリンを基材とする新規な分散性ナノ小胞コロイド系の製造及び適用
Document Type and Number:
Japanese Patent JPH07507783
Kind Code:
A
Abstract:
A nanovesicular system prepared by (1) preparing a liquid phase essentially consisting of a solution of cyclodextrin modified by acyl groups, and an oil in an organic solvent or solvent mixture; (2) preparing a second liquid phase essentially consisting of water or an aqueous mixture optionally containing one or more surfactants, one of said phases (1) and (2) optionally having an active molecule added thereto; and (3) gently stirring one of the liquid phases resulting from (1) or (2) into the other in order to obtain, almost instantaneously, a colloidal solution of modified cyclodextrin nanocapsules containing oil and optionally said active molecule. If required, all or part of the solvent or solvent mixture and all or part of the water or aqueous mixture may be removed. Said system may be used as a carrier for pharmaceuticals, cosmetics, chemicals, etc.
Inventors:
Skiva, Mohammed
Boucheijiub, douni
Hushey, Athem
Dwarf Bean, Jiyang-Filip
Deussienne, Dominsk
France, France
Boucheijiub, douni
Hushey, Athem
Dwarf Bean, Jiyang-Filip
Deussienne, Dominsk
France, France
Application Number:
JP50120294A
Publication Date:
August 31, 1995
Filing Date:
June 16, 1993
Export Citation:
Assignee:
CENTRE NAT RECH SCIENT (FR)
International Classes:
A61K9/51; A61K47/40; A61K47/48; B01J13/04; B01J13/08; A61J3/07; (IPC1-7): A61K9/51; A61J3/07; A61K47/40; B01J13/04; B01J13/08
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)