Title:
【発明の名称】JNK阻害剤としてのピラゾロアントロン及びその誘導体並びにそれらの組成物
Document Type and Number:
Japanese Patent JP2003532626
Kind Code:
A
Abstract:
Compounds having activity as selective inhibitors of JNK are disclosed. The compounds of this invention are pyrazoloanthrone and derivatives thereof having structure (I) wherein R1 and R2 are as defined herein. Such compounds have utility in the treatment of a wide range of conditions that are responsive to JNK inhibition. Thus, methods of treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more compounds of the above compounds.
Inventors:
Bennett, Bridon, Elle.
Berg Watt, Shri Pad, S.
Manning, Anthony, M.
Murray, Bryon, W.
O'Leary, Aoin, Sea.
Yoshitaka Sato
Berg Watt, Shri Pad, S.
Manning, Anthony, M.
Murray, Bryon, W.
O'Leary, Aoin, Sea.
Yoshitaka Sato
Application Number:
JP2001517507A
Publication Date:
November 05, 2003
Filing Date:
August 19, 2000
Export Citation:
Assignee:
Signal Pharmaceuticals, Incorporated
International Classes:
C07D231/54; A61K31/415; A61K31/416; A61K31/4439; A61K31/454; A61K31/5377; A61P1/04; A61P1/16; A61P9/10; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P19/08; A61P21/02; A61P25/00; A61P25/02; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P29/00; A61P35/00; A61P37/00; A61P37/06; A61P43/00; C07D401/04; C07D401/12; C07D409/12; C07D413/04; C07D; (IPC1-7): C07D231/54; A61K31/416; A61K31/4439; A61K31/454; A61K31/5377; A61P1/04; A61P1/16; A61P9/10; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P19/08; A61P21/02; A61P25/00; A61P25/02; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P29/00; A61P35/00; A61P37/00; A61P37/06; A61P43/00; C07D401/12; C07D409/12
Attorney, Agent or Firm:
Yusuke Hiraki (2 outside)