Title:
【発明の名称】光学活性アミンのラセミ化
Document Type and Number:
Japanese Patent JP2002539086
Kind Code:
A
Abstract:
A process for the preparation of racemic amines of the formula I where R1 and R2 are different and R1, R2, R3 are alkyl, cycloalkyl, arylalkyl, aryl, heteroaryl and heterocyclic radicals and R3 can also be hydrogen, where the radicals can bear substituents selected from the group consisting of alkyl, cycloalkyl, alkoxy, aryloxy, amino, alkylamino and dialkylamino, which comprises simultaneously reacting in situ the corresponding optically active amine I and the secondary alcohol of the formula II and/or the unsymmetrical ketone of the formula III and the amine of the formula R3NH2 in the presence of hydrogen and a hydrogenation catalyst or dehydrogenation catalyst at elevated temperature.
Inventors:
Hartmut Reichers
Joachim Jimon
Artur Hane
Andreas Kramer
Frank Funke
Wolfgang Siegel
Christoph Nubling
Joachim Jimon
Artur Hane
Andreas Kramer
Frank Funke
Wolfgang Siegel
Christoph Nubling
Application Number:
JP2000598466A
Publication Date:
November 19, 2002
Filing Date:
May 10, 1999
Export Citation:
Assignee:
BASF Akchen Gezel Shaft
International Classes:
C07B55/00; C07B57/00; C07B61/00; C07C209/68; C07C209/88; C07C213/02; C07C213/08; B01J23/755; C07C217/08; C07C211/03; (IPC1-7): C07C213/02; B01J23/755; C07C217/08
Attorney, Agent or Firm:
Toshio Yano (4 outside)