Title:
【発明の名称】放射線標識化キレート
Document Type and Number:
Japanese Patent JP2752355
Kind Code:
B2
Abstract:
Diphosphonate-derivatized macromolecules, such as proteins, suitable for use as technetium-99m-based scanning agents and as anticalcification agents are disclosed. The scanning agents are prepared by combining Tc-99m in a +3, +4 and/or +5 oxidation state with the diphosphonate-derived macromolecules. Also disclosed are pharmaceutical compositions containing these diphosphonate-derivatized macromolecules and methods for scintigraphic imaging using these diphosphonate-derivatized macromolecules labeled with Tc-99m.
Inventors:
JEEMUZU JON BENEDEIKUTO
CHAARUZU REIMONDO DEEGENHARUTO
JEEMUZU UIRIAMU HOOZAA
CHAARUZU REIMONDO DEEGENHARUTO
JEEMUZU UIRIAMU HOOZAA
Application Number:
JP15135786A
Publication Date:
May 18, 1998
Filing Date:
June 27, 1986
Export Citation:
Assignee:
PUROKUTAA ANDO GYANBURU CO ZA
International Classes:
A61K9/14; A61K9/19; A61K39/395; A61K41/00; A61K47/48; A61K51/00; A61K51/04; A61K51/06; A61K51/10; C07F9/38; C07F9/40; C07K1/13; C07K2/00; C07K14/435; C07K14/575; C07K14/76; C07K16/00; C08B37/00; C08F8/40; C08F8/42; C08F16/02; C08F16/06; C08F16/38; C08F20/10; C08F20/26; C08F22/06; C08F22/10; C08F120/04; C08G65/02; C08G65/08; C08G69/00; C08G73/04; C08G83/00; C08G85/00; C08H1/00; G01N33/58; G01N33/60; (IPC1-7): C07K2/00; A61K51/00; C07F9/38; C07K1/13; C07K14/435; C08B37/00; G01N33/60
Domestic Patent References:
| JP5829718A | ||||
| JP56164123A |
Attorney, Agent or Firm:
Kazuo Sato (2 outside)