Title:
【発明の名称】マラリア原虫MSP―1のC末端断片を含む組換えタンパク質
Document Type and Number:
Japanese Patent JP2000506381
Kind Code:
A
Abstract:
The invention relates to a recombinant protein fabricated in a baculovirus system, of which the essential constitutive polypeptide sequence is that of a C-terminal fragment of 42 kilodaltons (p42) of the surface protein 1 (protein MSP-1) of the merozoite form of a parasite of the Plasmodium type, particularly Plasmodium falciparum, which is infectious for humans, said p42 fragment being particularly deleted of its region II and, if necessary, also of its region III. Said recombinant protein is applicable to the production of vaccines against malaria.
Inventors:
Longercle Andre, Surry
Charles, Ross
Nato, Faridabano
Barnwell, John, W
Mendis, Kamini
Charles, Ross
Nato, Faridabano
Barnwell, John, W
Mendis, Kamini
Application Number:
JP52905897A
Publication Date:
May 30, 2000
Filing Date:
February 14, 1997
Export Citation:
Assignee:
Institute Pasteur
New York University
New York University
International Classes:
C12N15/02; A61K31/00; A61K39/015; A61P33/00; A61P33/06; C07K1/22; C07K14/445; C07K16/20; C12N5/10; C12N5/18; C12N15/09; C12N15/30; C12N15/86; C12P21/08; G01N33/569; A61K39/00; (IPC1-7): C12N15/09; A61P33/06; A61K39/015; C07K14/445; C07K16/20; C12N5/10; C12N15/02; G01N33/569
Attorney, Agent or Firm:
Yoshitaka Sonoda (1 outside)
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