Title:
【発明の名称】リボザイム
Document Type and Number:
Japanese Patent JP3046318
Kind Code:
B2
Abstract:
Synthetic RNA molecules having highly specific endoribonuclease activity (hereinafter referred to as "ribozymes") are described. The ribozymes comprise a hybridizing region which is complementary in nucleotide sequence to at least part of a target RNA, and a catalytic region which is adapted to cleave the target RNA. Methods for inactivating RNA, and compositions containing ribozymes are also described.
Inventors:
Haserov, James Philip
Jar rack, wayne reel
Jennings, Philip Anthony
Cameron, Fiona Helen
Jar rack, wayne reel
Jennings, Philip Anthony
Cameron, Fiona Helen
Application Number:
JP50027988A
Publication Date:
May 29, 2000
Filing Date:
December 14, 1988
Export Citation:
Assignee:
Gene Sears Pty Limited
International Classes:
A01N57/16; A01N63/60; A61K31/70; A61K31/7105; C12N9/22; A61K39/235; A61K39/285; A61P31/12; C07H21/02; C12N1/20; C12N5/02; C12N5/10; C12N15/00; C12N15/09; C12N15/113; C12N15/52; C12N15/82; C12P19/34; A61K38/00; A61K; C07H; (IPC1-7): C12N15/09; A61K31/7105; A61P31/12; C07H21/02; C12N5/10
Other References:
Ｎａｔｕｒｅ，３２４（４），Ｐ．４２９−４３３（１９８６）
Ｎａｔｕｒｅ，３２８（１３），Ｐ．５９６−６００（１９８７）
Ｎａｔｕｒｅ，３２８（１３），Ｐ．５９６−６００（１９８７）
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)