Title:
【発明の名称】可溶性T細胞受容体
Document Type and Number:
Japanese Patent JP2002515244
Kind Code:
A
Abstract:
The present invention relates to a synthetic multivalent T cell receptor complex for binding to a MHC-peptide complex, which multivalent T cell receptor complex comprises a plurality of T cell receptors specific for the MHC-peptide complex. It is preferred that the T cell receptors are refolded recombinant soluble T cell receptors. The synthetic multivalent T cell receptor complex can be used for delivering therapeutic agents or for detecting MHC-peptide complexes, and methods for such uses are also provided.
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Inventors:
Jacobsen, Bent, Kirsten
Bell, John, Eving
Gao, George, Who
Willcox, Benjamin, Ernest
Vaulter, jonathan, michael
Bell, John, Eving
Gao, George, Who
Willcox, Benjamin, Ernest
Vaulter, jonathan, michael
Application Number:
JP2000549728A
Publication Date:
May 28, 2002
Filing Date:
May 19, 1999
Export Citation:
Assignee:
Avidex Limited
International Classes:
A61K9/127; A61K47/48; G01N33/68; C07K14/725; C07K19/00; C12N15/09; C12N15/12; C12P21/02; G01N33/569; A61K38/00; C07K; C12N; (IPC1-7): C12N15/09; C07K14/725; C12P21/02
Attorney, Agent or Firm:
Mikio Hatta (4 outside)