Title:
【発明の名称】特異的結合物質
Document Type and Number:
Japanese Patent JPH05501357
Kind Code:
A
Abstract:
A reshaped human antibody or reshaped human antibody fragment having specificity for human placental alkaline phosphatase (PLAP) is produced by transferring the complementarity determining regions (CDRs) from a murine anti-PLAP hybridoma cell line H17E2 into a human antibody variable region framework. The reshaped molecule can be used in the treatment or diagnosis of cancer
Inventors:
Marthaine Elisa, Barhoeien
Application Number:
JP51580190A
Publication Date:
March 18, 1993
Filing Date:
November 14, 1990
Export Citation:
Assignee:
Unilever Namrose Rose Bennaught Sharp
International Classes:
A61K39/395; C07K7/06; C07K7/08; C07K16/00; C12N1/21; C12N5/10; C12N15/09; C12N15/13; C12P21/08; G01N33/53; G01N33/563; G01N33/573; G01N33/574; A61K38/00; C12R1/19; C12R1/91; (IPC1-7): A61K39/395; C07K7/06; C07K7/08; C07K99/00; C12N1/21; C12N5/10; C12N15/13; C12P21/08; G01N33/53; G01N33/563; G01N33/573; G01N33/574
Attorney, Agent or Firm:
Yoshio Kawaguchi (4 outside)