Title:
【発明の名称】抗生物質抵抗性感染の処置のための置換芳香族化合物
Document Type and Number:
Japanese Patent JP2002507557
Kind Code:
A
Abstract:
This invention relates to compounds of the general formula: wherein A is a aromatic hydrocarbon ring system and R 1 is a carbon bound directly to an oxygen and is also bound to a nitrogen through a saturated carbon and wherein at least one of R 2 , R 3 and R 4 is an electron-rich substituent. The active agents are useful for treating patients suffering from infections including gram positive organisms, such as streptococcus, staphylococcus, anthracis, gram negative bacteria such as neisseria species, yeasts and mycobacterium. They are effective against strains which have shown resistance to other antimicrobial agents.
Inventors:
Ellis, William Wye.
Application Number:
JP2000537515A
Publication Date:
March 12, 2002
Filing Date:
March 25, 1999
Export Citation:
Assignee:
Department of the Army, USS Government
International Classes:
A61K31/137; A61K31/424; A61K31/4458; A61K45/00; A61P31/04; A61P31/10; C07C215/28; C07C215/30; C07D211/22; C07D498/04; (IPC1-7): A61K31/137; A61K31/424; A61K31/4458; A61K45/00; A61P31/04; A61P31/10; C07D211/22
Attorney, Agent or Firm:
Shusaku Yamamoto