Title:
【発明の名称】グルココルチコイド的性質及び抗炎症性を有する,含硫アミノ酸又は非含硫アミノ酸と△―4―プレグネン―3,20―ジオン誘導体又は△―1,4―プレグナジエン―3,20―ジオン誘導体との結合合成化合物,製造方法,それ等を含む医薬組成物,薬理活性及び使用
Document Type and Number:
Japanese Patent JP2667418
Kind Code:
B2
Abstract:
PCT No. PCT/FR87/00244 Sec. 371 Date Feb. 24, 1988 Sec. 102(e) Date Feb. 24, 1988 PCT Filed Jun. 24, 1987 PCT Pub. No. WO88/00202 PCT Pub. Date Jan. 14, 1988.Compounds obtained from the associative synthesis of sulfur-containing or sulfur-free amino acids with derivatives of DELTA -4-pregnene-3,20-dione or with derivatives of DELTA -1,4-pregnadiene-3,20-dione of the general formulas (I), (II) and (III), having glucocorticoidal and anti-inflammatory properties have been prepared and tested. Pharmaceutical compositions, medicaments containing them as well as their applications are claimed, particularly in the cutaneous and ophthalmic fields. (I) (II) (III)
Inventors:
Millioni, Catouline
F.T.Miopros, Constantin
Koscille, Bernard
Jung, Louis
Jung, Jiang
F.T.Miopros, Constantin
Koscille, Bernard
Jung, Louis
Jung, Jiang
Application Number:
JP50378687A
Publication Date:
October 27, 1997
Filing Date:
June 24, 1987
Export Citation:
Assignee:
Universite Louis Pastor Dou Strasbourg
International Classes:
A61K31/58; A61P5/38; A61P29/00; A61K31/57; C07J1/00; C07J41/00; C07J43/00; (IPC1-7): C07J41/00; A61K31/57; C07J43/00
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)